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Article

Identification of ANKRD11 as a p53 coactivator.

Journal of cell science - 1 Nov 2008

Neilsen Paul M, Cheney Kelly M, Li Chia-Wei, Chen J Don, Cawrse Jacqueline E, Schulz Renée B, Powell Jason A, Kumar Raman, Callen David F

Abstract excerpt

The ability of p53 to act as a transcription factor is critical for its function as a tumor suppressor. Ankyrin repeat domain 11, ANKRD11 (also known as ANR11 or ANCO1), was found to be a novel p53-interacting protein that enhanced the transcriptional activity of p53. ANKRD11 expression was shown to be downregulated in breast cancer cell lines. Restoration of ANKRD11 expression in MCF-7 (wild-type p53) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18840648
DOI: 10.1242/jcs.026351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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