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Article

Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma.

Cancer letters - 8 Nov 2007

Pasquali Lorenzo, Bedeir Ahmed, Ringquist Steven, Styche Alexis, Bhargava Rohit, Trucco Giuliana

Abstract excerpt

Epigenetic silencing of specific genes is associated with cancer progression. CpG islands are present at higher frequency in promoter regions, their methylation leading to gene underexpression. Pyrosequencing provides sequencing analysis of genetic markers, e.g., single nucleotide polymorphisms and DNA methylation. We investigated methylation levels of a spectrum of neoplastic breast lesions, ranging from...

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Source

Identifiers

PMID: 17706863
DOI: 10.1016/j.canlet.2007.07.010

Genes

GSTP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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