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Article

Exercise tames the wild side of the Myc network: a hypothesis

25 Apr 2012

Abstract excerpt

We propose that the well-documented therapeutic actions of repeated physical activities over human lifespan are mediated by the rapidly turning over proto-oncogenic Myc (myelocytomatosis) network of transcription factors. This transcription factor network is unique in utilizing promoter and epigenomic (acetylation/deacetylation, methylation/demethylation) mechanisms for controlling genes that include those...

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PMID: 22535747
DOI: 10.1152/ajpendo.00027.2012

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