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Article

Metabolic reprogramming: a bridge between aging and tumorigenesis

5 Jun 2022

Abstract excerpt

Aging is the most robust risk factor for cancer development, with more than 60% of cancers occurring in those aged 60 and above. However, how aging and tumorigenesis are intertwined is poorly understood and a matter of significant debate. Metabolic changes are hallmarks of both aging and tumorigenesis. The deleterious consequences of aging include dysfunctional cellular processes, the build-up of metabolic...

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Autophagy in Disease and Therapy
Cancer, Hypoxia, and Metabolism
Epigenetics and DNA Methylation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35666002
DOI: 10.1002/1878-0261.13261

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