Article

The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates <i>MYC</i> as a Hypertrophic Regulator That is Sufficient for Growth

2024-03-27

Abstract excerpt

Molecular control of recovery after exercise in muscle is temporally dynamic. A time course of biopsies around resistance exercise (RE) combined with -omics is necessary to better comprehend the molecular contributions of skeletal muscle adaptation in humans. Vastus lateralis biopsies before and 30 minutes, 3-, 8-, and 24-hours after acute RE were collected. A time-point matched biopsy-only group was also included...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cfa329e6-fd7e-5300-ba99-e1d54209d7f6
DOI: 10.1101/2024.03.26.586857

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates <i>MYC</i> as a Hypertrophic Regulator That is Sufficient for GrowthDOI 10.1101/2024.03.26.586857Read

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growthSemantic proximity Read

Comparative Transcriptome and Methylome Analysis in Human Skeletal Muscle Anabolism, Hypertrophy and Epigenetic MemorySemantic proximity Read

Integrative Multi-omics Analysis of the Human Skeletal Muscle Response to Endurance or Resistance Exercise: Findings from the Molecular Transducers of Physical Activity Consortium (MoTrPAC)Semantic proximity Read

A history of omics discoveries reveals the correlates and mechanisms of loading-induced hypertrophy in adult skeletal muscle. 2024 CaMPS young investigator award invited reviewSemantic proximity Read

Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodellingSemantic proximity Read

Adaptation of the transcriptional response to resistance exercise over 4 weeks of daily training.Semantic proximity Read

Human Skeletal Muscle Possesses an Epigenetic Memory of HypertrophySemantic proximity Read

A muscle exercise research revolution powered by -omics at single cell and nucleus resolutionSemantic proximity Read

Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscleSemantic proximity Read

Cluster analysis reveals differential transcript profiles associated with resistance training-induced human skeletal muscle hypertrophySemantic proximity Read

Combined aerobic and resistance exercise training alters the spatial transcriptome of skeletal muscle in young adultsSemantic proximity Read