Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunological aspects in chronic lymphocytic leukemia (CLL) development

11 Apr 2012

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is unique among B cell malignancies in that the malignant clones can be featured either somatically mutated or unmutated IGVH genes. CLL cells that express unmutated immunoglobulin variable domains likely underwent final development prior to their entry into the germinal center, whereas those that express mutated variable domains likely transited through the germinal center and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Immunodeficiency and Autoimmune Disorders
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22526361
DOI: 10.1007/s00277-012-1460-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunological aspects in chronic lymphocytic leukemia (CLL) developmentPMID 22526361Read ↗

Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease?Semantic proximity Read ↗

The role of B cell receptor stimulation in CLL pathogenesis.Semantic proximity Read ↗

The origin of B-cell chronic lymphocytic leukemia.Semantic proximity Read ↗

Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.Semantic proximity Read ↗

Antigen stimulation in the development of chronic lymphocytic leukemia.Semantic proximity Read ↗

Cellular origin and pathophysiology of chronic lymphocytic leukemia.Semantic proximity Read ↗

A heterogeneous pool of tumor precursor cells with self-replenishing and tumor-originating properties in early pathogenesis of Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Pathophysiology of chronic lymphocytic leukemia and human B1 cell development.Semantic proximity Read ↗

The Pathogenesis of Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and OxidationSemantic proximity Read ↗

Chronic lymphocytic leukemia: revelations from the B-cell receptorSemantic proximity Read ↗

[Molecular biology of CLL].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.