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Article

Pathophysiology of chronic lymphocytic leukemia and human B1 cell development.

International journal of hematology - 1 May 2020

Kikushige Yoshikane

Abstract excerpt

Chronic lymphocytic leukemia (CLL), the most frequent type of leukemia in adults, is a lymphoproliferative disease characterized by the clonal expansion of mature CD5+ B cells in peripheral blood, bone marrow, and secondary lymphoid tissues. Over the past decade, substantial advances have been made in understanding the pathogenesis of CLL, including the identification of recurrent mutations, and clarification of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31797231
DOI: 10.1007/s12185-019-02788-7

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