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Article

Critical metabolic roles of β-cell M3 muscarinic acetylcholine receptors.

Life sciences - 27 Nov 2012

Ruiz de Azua Inigo, Gautam Dinesh, Jain Shalini, Guettier Jean-Marc, Wess Jürgen

Abstract excerpt

Muscarinic acetylcholine (ACh) receptors (mAChRs; M(1)-M(5)) regulate the activity of an extraordinarily large number of important physiological processes. We and others previously demonstrated that pancreatic β-cells are endowed with M(3) mAChRs which are linked to G proteins of the G(q) family. The activation of these receptors by ACh or other muscarinic agonists leads to the augmentation of glucose-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22525375
DOI: 10.1016/j.lfs.2012.04.010
PMCID: PMC3568704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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