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Article

Logistic Bayesian LASSO for genetic association analysis of data from complex sampling designs.

Journal of human genetics - 1 Sept 2017

Zhang Yuan, Hofmann Jonathan N, Purdue Mark P, Lin Shili, Biswas Swati

Abstract excerpt

Detecting gene-environment interactions with rare variants is critical in dissecting the etiology of common diseases. Interactions with rare haplotype variants (rHTVs) are of particular interest. At the same time, complex sampling designs, such as stratified random sampling, are becoming increasingly popular for designing case-control studies, especially for recruiting controls. The US Kidney Cancer Study (KCS)...

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PMID: 28424482
DOI: 10.1038/jhg.2017.43
PMCID: PMC5572548

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