Article
Predicting white matter integrity from multiple common genetic variants.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2012
Kohannim Omid, Jahanshad Neda, Braskie Meredith N, Stein Jason L, Chiang Ming-Chang, Reese April H, Hibar Derrek P, Toga Arthur W, McMahon Katie L, de Zubicaray Greig I, Medland Sarah E, Montgomery Grant W, Martin Nicholas G, Wright Margaret J, Thompson Paul M
Abstract excerpt
Several common genetic variants have recently been discovered that appear to influence white matter microstructure, as measured by diffusion tensor imaging (DTI). Each genetic variant explains only a small proportion of the variance in brain microstructure, so we set out to explore their combined effect on the white matter integrity of the corpus callosum. We measured six common candidate single-nucleotide...
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