Article
Relationship of a variant in the NTRK1 gene to white matter microstructure in young adults.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 25 Apr 2012
Braskie Meredith N, Jahanshad Neda, Stein Jason L, Barysheva Marina, Johnson Kori, McMahon Katie L, de Zubicaray Greig I, Martin Nicholas G, Wright Margaret J, Ringman John M, Toga Arthur W, Thompson Paul M
Abstract excerpt
The NTRK1 gene (also known as TRKA) encodes a high-affinity receptor for NGF, a neurotrophin involved in nervous system development and myelination. NTRK1 has been implicated in neurological function via links between the T allele at rs6336 (NTRK1-T) and schizophrenia risk. A variant in the neurotrophin gene, BDNF, was previously associated with white matter integrity in young adults, highlighting the importance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
