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Article

Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n = 17,706).

Molecular psychiatry - 1 Aug 2021

Zhao Bingxin, Zhang Jingwen, Ibrahim Joseph G, Luo Tianyou, Santelli Rebecca C, Li Yun, Li Tengfei, Shan Yue, Zhu Ziliang, Zhou Fan, Liao Huiling, Nichols Thomas E, Zhu Hongtu

Abstract excerpt

Individual variations of white matter (WM) tracts are known to be associated with various cognitive and neuropsychiatric traits. Diffusion tensor imaging (DTI) and genome-wide single-nucleotide polymorphism (SNP) data from 17,706 UK Biobank participants offer the opportunity to identify novel genetic variants of WM tracts and explore the genetic overlap with other brain-related complex traits. We analyzed the...

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Identifiers

PMID: 31666681
DOI: 10.1038/s41380-019-0569-z
PMCID: PMC7190426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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