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Genetic architecture of the white matter connectome of the human brain

2022-05-11

Abstract excerpt

White matter tracts form the structural basis of large-scale functional networks in the human brain. We applied brain-wide tractography to diffusion images from 30,810 adult participants (UK Biobank), and found significant heritability for 90 regional connectivity measures and 851 tract-wise connectivity measures. Multivariate genome-wide association analyses identified 355 independently associated lead SNPs acros...

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Literature Corpus work
3a393ced-8c4f-5f12-af16-834a1d60c03d
DOI
10.1101/2022.05.10.491289
Open publication

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Genetic architecture of the white matter connectome of the human brainDOI 10.1101/2022.05.10.491289
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