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Article

Genetics of brain fiber architecture and intellectual performance.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 18 Feb 2009

Chiang Ming-Chang, Barysheva Marina, Shattuck David W, Lee Agatha D, Madsen Sarah K, Avedissian Christina, Klunder Andrea D, Toga Arthur W, McMahon Katie L, de Zubicaray Greig I, Wright Margaret J, Srivastava Anuj, Balov Nikolay, Thompson Paul M

Abstract excerpt

The study is the first to analyze genetic and environmental factors that affect brain fiber architecture and its genetic linkage with cognitive function. We assessed white matter integrity voxelwise using diffusion tensor imaging at high magnetic field (4 Tesla), in 92 identical and fraternal twins. White matter integrity, quantified using fractional anisotropy (FA), was used to fit structural equation models...

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Identifiers

PMID: 19228974
DOI: 10.1523/JNEUROSCI.4184-08.2009
PMCID: PMC2773128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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