Article
Peroxisome proliferator-activated receptor delta (PPARD) genetic variation and type 2 diabetes in middle-aged Chinese women.
Annals of human genetics - 1 Sept 2011
Villegas Raquel, Williams Scott, Gao Yutang, Cai Qiuyin, Li Honglan, Elasy Tom, Cai Hui, Edwards Todd, Xiang Yong-Bing, Zheng Wei, Long Jirong, Ou Shu Xiao
Abstract excerpt
Animal studies have shown that the peroxime proliferator-activated receptor delta (PPARD) gene regulates glucose metabolism and insulin sensitivity. Genetic variation in the PPARD gene might affect physical endurance and has been associated with obesity. We investigated the independent and modifying effect of variants in the PPARD gene with exercise participation and body mass index (BMI) on type 2 diabetes...
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