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Article

Genetics of clusterin isoform expression and Alzheimer's disease risk.

PloS one - 1 Jan 2012

Ling I-Fang, Bhongsatiern Jiraganya, Simpson James F, Fardo David W, Estus Steven

Abstract excerpt

The minor allele of rs11136000 within CLU is strongly associated with reduced Alzheimer's disease (AD) risk. The mechanism underlying this association is unclear. Here, we report that CLU1 and CLU2 are the two primary CLU isoforms in human brain; CLU1 and CLU2 share exons 2-9 but differ in exon 1...

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Identifiers

PMID: 22506010
DOI: 10.1371/journal.pone.0033923
PMCID: PMC3323613

Genes

CLU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22506010-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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