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Article

Alzheimer's risk variants in the clusterin gene are associated with alternative splicing.

Translational psychiatry - 1 Jan 2011

Szymanski M, Wang R, Bassett S S, Avramopoulos D

Abstract excerpt

Genetic variation in CLU encoding clusterin has been associated with Alzheimer's disease (AD) through replicated genome-wide studies, but the underlying mechanisms remain unknown. Following earlier reports that tightly regulated CLU alternative transcripts have different functions, we tested CLU...

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Identifiers

PMID: 21892414
DOI: 10.1038/tp.2011.17
PMCID: PMC3165035

Genes

CLU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-21892414-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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