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Article

No association between the insulin degrading enzyme gene and Alzheimer's disease in a Japanese population.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Feb 2004

Sakai Ayumu, Ujike Hiroshi, Nakata Kenji, Takehisa Yasushi, Imamura Takaki, Uchida Naohiko, Kanzaki Akihiro, Yamamoto Mitsutoshi, Fujisawa Yoshikatsu, Okumura Kazuya, Kuroda Shigetoshi

Abstract excerpt

Susceptibility to Alzheimer's disease (AD) is thought to be regulated by multiple genetic factors. Recently, three independent studies have reported that loci on chromosome 10q are linked with AD, and the insulin degrading enzyme (IDE; MIM 146680) gene located on chromosome 10q23-q25; IDE is located close to the maker D10S583, which exhibits a maximum LOD score for late-onset AD. We examined seven polymorphisms...

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Source

Identifiers

PMID: 14755451
DOI: 10.1002/ajmg.b.20106

Genes

IDE
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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