Article
Effect of population stratification on false positive rates of population-based association analyses of quantitative traits.
Annals of human genetics - 1 May 2012
Haldar Tanushree, Ghosh Saurabh
Abstract excerpt
It is now well established that population stratification can result in spurious association findings in genetic case-control studies. However, very few studies have addressed similar issues for mapping quantitative traits. Because quantitative phenotypes are often precursors of clinical endpoint traits and carry more information on within-genotype trait variability, it has been argued that studying these...
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