Testing for genetic association in the presence of population stratification in genome-wide association studies.

Abstract excerpt

Genome-wide case-control association study is gaining popularity, thanks to the rapid development of modern genotyping technology. In such studies, population stratification is a potential concern especially when the number of study subjects is large as it can lead to seriously inflated false-positive rates. Current methods addressing this issue are still not completely immune to excess false positives. A simple...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biostatistics
• Share to Computer Simulation
• Share to False Positive Reactions