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Article

Genetic association with multiple traits in the presence of population stratification.

Genetic epidemiology - 1 Sept 2013

Yan Ting, Li Qizhai, Li Yuanzhang, Li Zhaohai, Zheng Gang

Abstract excerpt

Testing association between a genetic marker and multiple-dependent traits is a challenging task when both binary and quantitative traits are involved. The inverted regression model is a convenient method, in which the traits are treated as predictors although the genetic marker is an ordinal response. It is known that population stratification (PS) often affects population-based association studies. However, how...

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PMID: 23740720
DOI: 10.1002/gepi.21738

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