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Article

Population stratification and spurious allelic association.

Lancet (London, England) - 15 Feb 2003

Cardon Lon R, Palmer Lyle J

Abstract excerpt

Great efforts and expense have been expended in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Concomitantly, technology for detection and scoring of single nucleotide polymorphisms (SNPs) has undergone rapid development, extensive catalogues of SNPs across the genome have been constructed, and SNPs have been increasingly used as a means for investigation of the...

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PMID: 12598158
DOI: 10.1016/S0140-6736(03)12520-2

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