Article
Correlation of population parameters leading to power differences in association studies with population stratification.
Annals of human genetics - 1 Nov 2008
He Y, Jiang R, Fu W, Bergen A W, Swan G E, Jin L
Abstract excerpt
The power of statistical tests to measure effect sizes in the presence of population stratification is an important issue for the design and analysis of population-based association studies. Comparisons of statistical tests have shown that the power of different statistical approaches varies in different genetic scenarios. However, the impact of stratified population parameters on statistical power is not yet...
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