A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese.

doi:10.1093/infdis/jiq154

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese.

The Journal of infectious diseases - 1 Apr 2011

An Ping, Winkler Cheryl, Guan Li, O'Brien Stephen J, Zeng Zheng

Abstract excerpt

A recent genome-wide study showed that the single nucleotide polymorphisms (SNPs) in the HLA-DP region were associated with chronic hepatitis B virus (HBV) infection in Japanese and Thai persons. We tested the effects of HLA-DP SNPs for all major HBV outcomes in Han Chinese (n = 1742): HBV resistance, clearance, chronic infection, cirrhosis, and hepatocellular carcinoma. HLA - DPA1 rs3077 T was strongly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to China

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to HLA-DP alpha-Chains

Share to HLA-DP Antigens

Share to Immunity, Innate

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 21402545
DOI: 10.1093/infdis/jiq154
PMCID: PMC3068033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese.PMID 21402545Read ↗

Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.Semantic proximity Read ↗

Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development.Semantic proximity Read ↗

Genetic variants in human leukocyte antigen/DP-DQ influence both hepatitis B virus clearance and hepatocellular carcinoma development.Semantic proximity Read ↗

Relationship between HLA-DP gene polymorphisms and clearance of chronic hepatitis B virus infections: case-control study and meta-analysis.Semantic proximity Read ↗

Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population.Semantic proximity Read ↗

Role of HLA-DP polymorphisms on chronicity and disease activity of hepatitis B infection in Southern Chinese.Semantic proximity Read ↗

Association of the rs3077 and rs9277535 polymorphisms in HLA-DP with hepatitis B virus infection and spontaneous clearance: a meta-analysis.Semantic proximity Read ↗

Variation of HLA-DPB1 Gene in Hepatitis B InfectionSemantic proximity Read ↗

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.Semantic proximity Read ↗

HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations.Semantic proximity Read ↗

Variation and expression of HLA-DPB1 gene in HBV infection.Semantic proximity Read ↗

Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.