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Article

Influence of sex and genetic background on anxiety-related and stress-induced behaviour of prodynorphin-deficient mice.

PloS one - 1 Jan 2012

Kastenberger Iris, Lutsch Christian, Herzog Herbert, Schwarzer Christoph

Abstract excerpt

The role of dynorphin/kappa opioid receptors in epilepsy and addiction are well accepted, but their function in emotional control is not yet fully understood. Data obtained from different strains of prodynorphin (Pdyn)- and kappa opioid receptor (KOP)-deficient mice do not provide a consistent picture of the functions of Dyn/KOP in anxiety, suggesting the influence of testing conditions and/or genetic background....

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PMID: 22479578
DOI: 10.1371/journal.pone.0034251
PMCID: PMC3315500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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