Article
Early life environment determines the development of adult phobic-like fear responses in BALB/cAnN mice.
Genes, brain, and behavior - 1 Nov 2010
Thoeringer C K, Pfeiffer U J, Rammes G, Pamplona F A, Moosmang S, Wotjak C T
Abstract excerpt
Environmental factors may unleash genetically determined susceptibility to psychopathology. Great effort has been spent in identifying both the genetic basis and environmental sources of exaggerated fear in animal models of anxiety disorders. Here, we show that the origin of inbred mice, probably via subtle differences in breeding and rearing conditions, may have large consequences specifically on acquisition and...
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