Article
ARGONAUTE10 promotes the degradation of miR165/6 through the SDN1 and SDN2 exonucleases in Arabidopsis.
PLoS biology - 1 Feb 2017
Yu Yu, Ji Lijuan, Le Brandon H, Zhai Jixian, Chen Jiayi, Luscher Elizabeth, Gao Lei, Liu Chunyan, Cao Xiaofeng, Mo Beixin, Ma Jinbiao, Meyers Blake C, Chen Xuemei
Abstract excerpt
The degradation of small RNAs in plants and animals is associated with small RNA 3' truncation and 3' uridylation and thus relies on exonucleases and nucleotidyl transferases. ARGONAUTE (AGO) proteins associate with small RNAs in vivo and are essential for not only the activities but also the stability of small RNAs. AGO1 is the microRNA (miRNA) effector in Arabidopsis, and its closest homolog, AGO10, maintains...
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