Article
Plant microRNAs display differential 3' truncation and tailing modifications that are ARGONAUTE1 dependent and conserved across species.
The Plant cell - 1 Jul 2013
Zhai Jixian, Zhao Yuanyuan, Simon Stacey A, Huang Sheng, Petsch Katherine, Arikit Siwaret, Pillay Manoj, Ji Lijuan, Xie Meng, Cao Xiaofeng, Yu Bin, Timmermans Marja, Yang Bing, Chen Xuemei, Meyers Blake C
Abstract excerpt
Plant small RNAs are 3' methylated by the methyltransferase HUA1 ENHANCER1 (HEN1). In plant hen1 mutants, 3' modifications of small RNAs, including oligo-uridylation (tailing), are associated with accelerated degradation of microRNAs (miRNAs). By sequencing small RNAs of the wild type and hen1 mutants from Arabidopsis thaliana, rice (Oryza sativa), and maize (Zea mays), we found 3' truncation prior to tailing is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.