Article
A phasing and imputation method for pedigreed populations that results in a single-stage genomic evaluation.
Genetics, selection, evolution : GSE - 19 Jun 2012
Hickey John M, Kinghorn Brian P, Tier Bruce, van der Werf Julius H J, Cleveland Matthew A
Abstract excerpt
BACKGROUND: Efficient, robust, and accurate genotype imputation algorithms make large-scale application of genomic selection cost effective. An algorithm that imputes alleles or allele probabilities for all animals in the pedigree and for all genotyped single nucleotide polymorphisms (SNP) provides a framework to combine all pedigree, genomic, and phenotypic information into a single-stage genomic evaluation....
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