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Article

Imputation of missing genotypes from sparse to high density using long-range phasing.

Genetics - 1 Sept 2011

Daetwyler Hans D, Wiggans George R, Hayes Ben J, Woolliams John A, Goddard Mike E

Abstract excerpt

Related individuals share potentially long chromosome segments that trace to a common ancestor. We describe a phasing algorithm (ChromoPhase) that utilizes this characteristic of finite populations to phase large sections of a chromosome. In addition to phasing, our method imputes missing genotypes in individuals genotyped at lower marker density when more densely genotyped relatives are available. ChromoPhase...

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Identifiers

PMID: 21705746
DOI: 10.1534/genetics.111.128082
PMCID: PMC3176129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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