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Article

CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.

American journal of respiratory cell and molecular biology - 1 Aug 2012

Hardin Megan, Zielinski Jan, Wan Emily S, Hersh Craig P, Castaldi Peter J, Schwinder Eric, Hawrylkiewicz Iwona, Sliwinski Pawel, Cho Michael H, Silverman Edwin K

Abstract excerpt

We examined the association between single-nucleotide polymorphisms (SNPs) previously associated with chronic obstructive pulmonary disease (COPD) and/or lung function with COPD and COPD-related phenotypes in a novel cohort of patients with severe to very severe COPD. We examined 315 cases of COPD and 330 Caucasian control smokers from Poland. We included three SNPs previously associated with COPD: rs7671167...

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Source

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Identifiers

PMID: 22461431
DOI: 10.1165/rcmb.2012-0011OC
PMCID: PMC3423462

Genes

ADCY2
CHRNA3
AGER
INTS12
THSD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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