Article
Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline.
Respiratory research - 18 Apr 2015
Xie Jungang, Wu Hongxu, Xu Yuzhu, Wu Xiaojie, Liu Xue, Shang Jin, Zhao Jianping, Zhao Junling, Wang Jianmiao, Dela Cruz Charles S, Xiong Weining, Xu Yongjian
Abstract excerpt
BACKGROUND: To identify COPD associated gene susceptibility and lung function in a longitudinal cohort including COPD and subjects who were at risk for developing COPD, and to replicate this in two cross-sectional and longitudinal populations in Chinese Han population. METHODS: Three cohorts were recruited in this study, including an 18-year follow-up population (306 COPD and 743 control subjects) in one village...
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