Article
Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases.
Scientific reports - 27 Aug 2015
Ziółkowska-Suchanek Iwona, Mosor Maria, Gabryel Piotr, Grabicki Marcin, Żurawek Magdalena, Fichna Marta, Strauss Ewa, Batura-Gabryel Halina, Dyszkiewicz Wojciech, Nowak Jerzy
Abstract excerpt
Genome-wide association studies have identified loci at 15q25 (IREB2) and 4q22 (FAM13A), associated with lung cancer (LC) and chronic obstructive pulmonary disease (COPD). The aim of our research was to determine the association of IREB2 and FAM13A SNPs with LC and severe/very severe COPD patients. We examined IREB2 variants (rs2568494, rs2656069, rs10851906, rs13180) and FAM13A (rs1903003, , )...