Article
Association of IREB2 and CHRNA3/5 polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population.
Journal of human genetics - 26 Nov 2012
Zhou Haixia, Yang Jing, Li Dengxue, Xiao Jun, Wang Bo, Wang Lan, Ma Chunlan, Xu Sicheng, Ou Xuemei, Feng Yulin
Abstract excerpt
Genome-wide association studies and integrative genomics approaches have demonstrated significant associations between chronic obstructive pulmonary disease (COPD) and single-nucleotide polymorphisms (SNPs) in the chromosome 15q25 region that includes iron-responsive element binding protein 2 gene (IREB2) and CHRNA3/5 in non-Asian populations. We investigated whether IREB2 and CHRNA3/5 polymorphisms would be...
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