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Article

Widespread site-dependent buffering of human regulatory polymorphism.

PLoS genetics - 1 Jan 2012

Maurano Matthew T, Wang Hao, Kutyavin Tanya, Stamatoyannopoulos John A

Abstract excerpt

The average individual is expected to harbor thousands of variants within non-coding genomic regions involved in gene regulation. However, it is currently not possible to interpret reliably the functional consequences of genetic variation within any given transcription factor recognition sequence...

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Source

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Identifiers

PMID: 22457641
DOI: 10.1371/journal.pgen.1002599
PMCID: PMC3310774

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22457641-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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