Article
Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals.
Genome research - 1 Jan 2014
Battle Alexis, Mostafavi Sara, Zhu Xiaowei, Potash James B, Weissman Myrna M, McCormick Courtney, Haudenschild Christian D, Beckman Kenneth B, Shi Jianxin, Mei Rui, Urban Alexander E, Montgomery Stephen B, Levinson Douglas F, Koller Daphne
Abstract excerpt
Understanding the consequences of regulatory variation in the human genome remains a major challenge, with important implications for understanding gene regulation and interpreting the many disease-risk variants that fall outside of protein-coding regions. Here, we provide a direct window into the regulatory consequences of genetic variation by sequencing RNA from 922 genotyped individuals. We present a...
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