Article
[A comparison of direct sequencing and ARMS assay performance in EGFR mutation analysis of non-small cell lung cancer patients].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Aug 2014
Li Chenchen, Wu Jianzhong, Wang Zhuo, Feng Jifeng
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) inhibitors are mainly used for the targeted therapy of non-small cell lung cancer (NSCLC). Therefore, EGFR mutations should be detected to treat lung cancer. The aim of this study is to determine the detection rate of NSCLC in patients with EGFR gene mutations by conducting direct sequencing and ARMS assay. METHODS: A total of 451 patients who were diagnosed...
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