Article
[Value of detecting epidermal growth factor receptor mutations in non-small cell lung cancer tissue by TaqMan-amplification refractory mutation system].
Zhonghua yi xue za zhi - 12 Mar 2013
Dou Ya-ling, Qi Xiao-li, Xin Lun, Chen Dong, Zhang Hai-qing, Cui Quan-cai
Abstract excerpt
OBJECTIVE: To explore the value of detecting mutations on epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer (NSCLC) tissue by TaqMan-amplification refractory mutation system (TaqMan-ARMS). METHODS: TaqMan-ARMS and DNA sequencing were used to detect the EGFR exon 19 and 21 mutations in tumor tissues and the samples collected from 199 patients at 4 different 3A hospitals in Beijing from...
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