Article
[Detection of epidermal growth factor receptor gene mutations in non-small cell lung cancer using bi-loop probe specific primer quantitative PCR].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Oct 2011
Wang Li-shuai, Zhang Yu, Lu Xiao-jun, Lu Hua-jun, Zhou Lin, Wang Yong-sheng, Deng Lei, Huang Mei-juan, Peng Feng, Wang Jin, Ren Li, Hou Mei, Li Lu, Xu Yong, Ying Bin-wu, Lu You
Abstract excerpt
OBJECTIVE: To investigate the sensitivity of bi-loop probe and specific primer quantitative PCR (BPSP-qPCR) in the detection of epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer (NSCLC). METHODS: BPSP-qPCR was employed to examine the presence of mutations of EFGR exon 19 through 21. Correlation of the mutations with clinicopathological characteristics and types of tumor samples...
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