Article
[Detection of epidermal growth factor receptor mutations in non-small cell lung cancer by real-time PCR using TaqMan-MGB probes].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Feb 2007
Zhou Cai-Cun, Zhou Song-Wen, Pan Hong, Su Bo, Gao Zhi-Qiang
Abstract excerpt
OBJECTIVE: To investigate mutations of EGFR TK gene in non-small cell lung cancer (NSCLC) and the diagnostic value of the mutations assayed by real-time PCR using TaqMan-MGB probes. METHODS: Tyrosine kinase genes of EGFR (exons 18, 19 and 21) were amplified by PCR technology, and sequenced and an...
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