Article
Detection of Rare Mutations in EGFR-ARMS-PCR-Negative Lung Adenocarcinoma by Sanger Sequencing.
Yonsei medical journal - 1 Jan 2018
Liang Chaoyue, Wu Zhuolin, Gan Xiaohong, Liu Yuanbin, You You, Liu Chenxian, Zhou Chengzhi, Liang Ying, Mo Haiyun, Chen Allen M, Zhang Jiexia
Abstract excerpt
PURPOSE: This study aimed to identify potential epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer that went undetected by amplification refractory mutation system-Scorpion real-time PCR (ARMS-PCR). MATERIALS AND METHODS: A total of 200 specimens were obtained from the First Affiliated Hospital of Guangzhou Medical University from August 2014 to August 2015. In total, 100...
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