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Article

Genomics and successful aging: grounds for renewed optimism?

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 May 2012

Pilling L C, Harries L W, Powell J, Llewellyn D J, Ferrucci L, Melzer D

Abstract excerpt

BACKGROUND: Successful aging depends in part on delaying age-related disease onsets until later in life. Conditions including coronary artery disease, Alzheimer's disease, prostate cancer, and type 2 diabetes are moderately heritable. Genome-wide association studies have identified many risk associated single-nucleotide polymorphisms for these conditions, but much heritability remains unaccounted for....

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Identifiers

PMID: 22454374
DOI: 10.1093/gerona/gls091
PMCID: PMC3326244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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