Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomics of human health and aging.

Age (Dordrecht, Netherlands) - 1 Apr 2013

Kulminski Alexander M, Culminskaya Irina

Abstract excerpt

Despite notable progress of the candidate-gene and genome-wide association studies (GWAS), understanding the role of genes contributing to human health and lifespan is still very limited. We use the Framingham Heart Study to elucidate if recognizing the role of evolution and systemic processes in an aging organism could advance such studies. We combine throughput methods of GWAS with more detail methods typical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Linkage Disequilibrium
Share to Age of Onset
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apoptosis

Share to Cardiovascular Diseases

Share to Databases, Genetic

Share to Nervous System Diseases

Share to Proportional Hazards Models

Source

Open in PubMed Open full text

Identifiers

PMID: 22174011
DOI: 10.1007/s11357-011-9362-x
PMCID: PMC3592948

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomics of human health and aging.PMID 22174011Read ↗

Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges.Semantic proximity Read ↗

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.Semantic proximity Read ↗

Phenome and genome based studies into human ageing and longevity: An overview.Semantic proximity Read ↗

Multivariate genomic scan implicates novel loci and haem metabolism in human ageing.Semantic proximity Read ↗

LongevityMap: a database of human genetic variants associated with longevity.Semantic proximity Read ↗

Genetics of human longevity: From variants to genes to pathwaysSemantic proximity Read ↗

Genetics of the Leading Causes of Death in Human AgingSemantic proximity Read ↗

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.Semantic proximity Read ↗

Genetic evidence for common pathways in human age-related diseases.Semantic proximity Read ↗

Human aging in the post-GWAS era: further insights reveal potential regulatory variants.Semantic proximity Read ↗

Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality.Semantic proximity Read ↗

Identification of 12 genetic loci associated with human healthspanSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.