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Article

Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline.

Genes & development - 1 Feb 2006

Savitsky Mikhail, Kwon Dmitry, Georgiev Pavel, Kalmykova Alla, Gvozdev Vladimir

Abstract excerpt

Telomeres in Drosophila are maintained by transposition of specialized telomeric retroelements HeT-A, TAHRE, and TART instead of the short DNA repeats generated by telomerase in other eukaryotes. Here we implicate the RNA interference machinery in the control of Drosophila telomere length in ovaries. The abundance of telomeric retroelement transcripts is up-regulated owing to mutations in the spn-E and aub genes,...

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Source

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Identifiers

PMID: 16452506
DOI: 10.1101/gad.370206
PMCID: PMC1361705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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