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Article

tef: a mutation that causes telomere fusion and severe genome rearrangements in Drosophila melanogaster.

Chromosoma - 1 Apr 2001

Queiroz-Machado J, Perdigão J, Simões-Carvalho P, Herrmann S, Sunkel C E

Abstract excerpt

Telomeres are the stable ends of linear chromosomes in eukaryotes. These complex protein-nucleic acid structures are essential to maintain genomic stability and the integrity of linear chromosomes. We identified a new mutation in Drosophila that causes a high frequency of end-to-end fusions of chromosomes during mitosis and meiosis. Linear chromosomal ends appear to be essential for fusions to take place. These...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11398972
DOI: 10.1007/s004120000116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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