Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast Swd2 is essential because of antagonism between Set1 histone methyltransferase complex and APT (associated with Pta1) termination factor.

The Journal of biological chemistry - 4 May 2012

Soares Luis M, Buratowski Stephen

Abstract excerpt

The Set1 complex (also known as complex associated with Set1 or COMPASS) methylates histone H3 on lysine 4, with different levels of methylation affecting transcription by recruiting various factors to distinct regions of active genes. Neither Set1 nor its associated proteins are essential for viability with the notable exception of Swd2, a WD repeat protein that is also a subunit of the essential transcription...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Genes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

Share to Histones

Share to Immunoblotting

Share to Methylation

Share to Proton-Translocating ATPases

Share to Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22431730
DOI: 10.1074/jbc.M112.341412
PMCID: PMC3346109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast Swd2 is essential because of antagonism between Set1 histone methyltransferase complex and APT (associated with Pta1) termination factor.PMID 22431730Read ↗

Suppressor mutations that make the essential transcription factor Spn1/Iws1 dispensable in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

Opposing roles for Set2 and yFACT in regulating TBP binding at promoters.Semantic proximity Read ↗

Isw1 functions in parallel with the NuA4 and Swr1 complexes in stress-induced gene repression.Semantic proximity Read ↗

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation.Semantic proximity Read ↗

H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway.Semantic proximity Read ↗

Functional antagonism between Sas3 and Gcn5 acetyltransferases and ISWI chromatin remodelers.Semantic proximity Read ↗

The essential WD repeat protein Swd2 has dual functions in RNA polymerase II transcription termination and lysine 4 methylation of histone H3.Semantic proximity Read ↗

A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation.Semantic proximity Read ↗

Positive roles of SAS2 in DNA replication and transcriptional silencing in yeast.Semantic proximity Read ↗

Feedback control of Set1 protein levels is important for proper H3K4 methylation patterns.Semantic proximity Read ↗

A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation.Semantic proximity Read ↗

The role of Sas2, an acetyltransferase homologue of Saccharomyces cerevisiae, in silencing and ORC function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.