Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Are mouse models of human mycobacterial diseases relevant? Genetics says: 'yes!'.

Immunology - 1 Oct 2011

Apt Alexander S

Abstract excerpt

Relevance and accuracy of experimental mouse models of tuberculosis (TB) are the subject of constant debate. This article briefly reviews genetic aspects of this problem and provides a few examples of mycobacterial diseases with similar or identical genetic control in mice and humans. The two species display more similarities than differences regarding both genetics of susceptibility/severity of mycobacterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cation Transport Proteins
Share to Gene Knockout Techniques
Share to Immune System Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interferon Regulatory Factors

Share to Minor Histocompatibility Antigens

Share to Multifactorial Inheritance

Share to Trans-Activators

Share to Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 21896006
DOI: 10.1111/j.1365-2567.2011.03472.x
PMCID: PMC3194219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Are mouse models of human mycobacterial diseases relevant? Genetics says: 'yes!'.PMID 21896006Read ↗

Mouse models for the genetic study of tuberculosis susceptibility.Semantic proximity Read ↗

Host genetics in susceptibility to and severity of mycobacterial diseases.Semantic proximity Read ↗

Drug testing in mouse models of tuberculosis and nontuberculous mycobacterial infections.Semantic proximity Read ↗

Genetics of susceptibility to tuberculosis in humans.Semantic proximity Read ↗

Immunological roads diverged: mapping tuberculosis outcomes in mice.Semantic proximity Read ↗

Genetic Dissection of Immunity to Mycobacteria: The Human ModelSemantic proximity Read ↗

Genetic susceptibility to mycobacterial disease in humans.Semantic proximity Read ↗

[Tuberculosis: pathogenesis, immune responses and genetics of the host].Semantic proximity Read ↗

Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosisSemantic proximity Read ↗

[Genetics and immunity of tuberculosis].Semantic proximity Read ↗

Host genetics of mycobacterial diseases in mice and men: forward genetic studies of BCG-osis and tuberculosis.Semantic proximity Read ↗

Human genetics of mycobacterial disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.