Article
Virulence, immunopathology and transmissibility of selected strains of Mycobacterium tuberculosis in a murine model.
Immunology - 1 Sept 2009
Marquina-Castillo Brenda, García-García Lourdes, Ponce-de-León Alfredo, Jimenez-Corona Maria-Eugenia, Bobadilla-Del Valle Miriam, Cano-Arellano Bulmaro, Canizales-Quintero Sergio, Martinez-Gamboa Areli, Kato-Maeda Midori, Robertson Brian, Young Douglas, Small Peter, Schoolnik Gary, Sifuentes-Osornio Jose, Hernandez-Pando Rogelio
Abstract excerpt
After encounter with Mycobacterium tuberculosis, a series of non-uniform immune responses are triggered that define the course of the infection. Eight M. tuberculosis strains were selected from a prospective population-based study of pulmonary tuberculosis patients (1995-2003) based on relevant clinical/epidemiological patterns and tested in a well-characterized BALB/c mouse model of progressive pulmonary...
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