Article
Methods and resources to access mutation-dependent effects on cancer drug treatment.
Briefings in bioinformatics - 1 Dec 2020
Yao Hongcheng, Liang Qian, Qian Xinyi, Wang Junwen, Sham Pak Chung, Li Mulin Jun
Abstract excerpt
In clinical cancer treatment, genomic alterations would often affect the response of patients to anticancer drugs. Studies have shown that molecular features of tumors could be biomarkers predictive of sensitivity or resistance to anticancer agents, but the identification of actionable mutations are often constrained by the incomplete understanding of cancer genomes. Recent progresses of next-generation...
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