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Article

Infrequent p53 gene mutation but UV gradient-like p53 protein positivity in keloids.

Experimental dermatology - 1 Apr 2012

Heitzer Ellen, Seidl Hannes, Bambach Isabella, Schmidbauer Ulrike, Cerroni Lorenzo, Wolf Peter

Abstract excerpt

Keloids are characterized by extreme fibroblastic overgrowth of unknown pathogenesis after skin injury. Previous studies, mostly in non-Caucasian populations, suggest that p53 mutations may be involved. To substantiate this, we performed DNA sequence analysis of exons 4-8 of the p53 gene and immunohistochemical staining of p53 protein in archived keloidal tissue samples from 23 Caucasian patients. In contrast to...

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Identifiers

PMID: 22417303
DOI: 10.1111/j.1600-0625.2012.01450.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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